Filarial worms and their larvae are parasitic thread-like round nematodes that cause a group of tropical infectious disease called Filariasis (Philariasis). The larvae are transmitted to humans through a mosquito bite. Filariasis is characterized by fever, chills, headache, and skin lesions in the early stages and, if untreated, can progress to include gross enlargement of the limbs and genitalia in a condition called elephantiasis. The worms dwell within the lymphatic and subcutaneous tissues. Up to 170 million people worldwide in the tropical and subtropical areas of Southeast Asia, South America, Africa, and the islands of the Pacific are affected by this debilitating parasitic disease. While filariasis is rarely fatal, it is the second leading cause of permanent and long-term disability in the world.